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Influence of translation efficiency of homologous viral proteins on the endogenous presentation of CD8(+) T cell epitopes

A significant proportion of endogenously processed CD8(+) T cell epitopes are derived from newly synthesized proteins and rapidly degrading polypeptides (RDPs). It has been hypothesized that the generation of rapidly degrading polypeptides and CD8(+) T cell epitopes from these RDP precursors may be...

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Detalles Bibliográficos
Autores principales:	Tellam, Judy, Fogg, Mark H., Rist, Michael, Connolly, Geoff, Tscharke, David, Webb, Natasha, Heslop, Lea, Wang, Fred, Khanna, Rajiv
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137904/ https://www.ncbi.nlm.nih.gov/pubmed/17312009 http://dx.doi.org/10.1084/jem.20062508

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