α(E)β(7) integrin interaction with E-cadherin promotes antitumor CTL activity by triggering lytic granule polarization and exocytosis

Various T cell adhesion molecules and their cognate receptors on target cells promote T cell receptor (TCR)–mediated cell killing. In this report, we demonstrate that the interaction of epithelial cell marker E-cadherin with integrin α(E)(CD103)β(7), often expressed by tumor-infiltrating lymphocytes...

Descripción completa

Detalles Bibliográficos
Autores principales: Floc'h, Audrey Le, Jalil, Abdelali, Vergnon, Isabelle, Chansac, Béatrice Le Maux, Lazar, Vladimir, Bismuth, Georges, Chouaib, Salem, Mami-Chouaib, Fathia
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137907/
https://www.ncbi.nlm.nih.gov/pubmed/17325197
http://dx.doi.org/10.1084/jem.20061524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137907/
https://www.ncbi.nlm.nih.gov/pubmed/17325197
http://dx.doi.org/10.1084/jem.20061524

Ejemplares similares