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Virus-specific CD8(+) T cells accumulate near sensory nerve endings in genital skin during subclinical HSV-2 reactivation

Cytotoxic CD8(+) T cells play a critical role in controlling herpes simplex virus (HSV) infection and reactivation. However, little is known about the spatiotemporal dynamics of CD8(+) T cells during HSV lesion evolution or about their involvement in immune surveillance after lesion resolution. Usin...

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Detalles Bibliográficos
Autores principales: Zhu, Jia, Koelle, David M., Cao, Jianhong, Vazquez, Julio, Huang, Meei Li, Hladik, Florian, Wald, Anna, Corey, Lawrence
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137910/
https://www.ncbi.nlm.nih.gov/pubmed/17325200
http://dx.doi.org/10.1084/jem.20061792