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Tubulin Subunits Exist in an Activated Conformational State Generated and Maintained by Protein Cofactors

The production of native α/β tubulin heterodimer in vitro depends on the action of cytosolic chaperonin and several protein cofactors. We previously showed that four such cofactors (termed A, C, D, and E) together with native tubulin act on β-tubulin folding intermediates generated by the chaperonin...

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Detalles Bibliográficos
Autores principales: Tian, Guoling, Lewis, Sally A., Feierbach, Becket, Stearns, Timothy, Rommelaere, Heidi, Ampe, Christophe, Cowan, Nicholas J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138046/
https://www.ncbi.nlm.nih.gov/pubmed/9265649