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Gelsolin Modulates Phospholipase C Activity In Vivo through Phospholipid Binding

Gelsolin and CapG are actin regulatory proteins that remodel the cytoskeleton in response to phosphatidylinositol 4,5-bisphosphate (PIP(2)) and Ca(2+) during agonist stimulation. A physiologically relevant rise in Ca(2+) increases their affinity for PIP(2) and can promote significant interactions wi...

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Detalles Bibliográficos
Autores principales: Sun, Hui-qiao, Lin, Keng-mean, Yin, Helen L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138049/
https://www.ncbi.nlm.nih.gov/pubmed/9265648