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Regulation and Function of the CD3γ DxxxLL Motif: A Binding Site for Adaptor Protein-1 and Adaptor Protein-2 in Vitro

Several receptors are downregulated by internalization after ligand binding. Regulation of T cell receptor (TCR) expression is an important step in T cell activation, desensitization, and tolerance induction. One way T cells regulate TCR expression is by phosphorylation/dephosphorylation of the TCR...

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Detalles Bibliográficos
Autores principales: Dietrich, Jes, Kastrup, Jesper, Nielsen, Bodil L., Ødum, Niels, Geisler, Carsten
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138198/
https://www.ncbi.nlm.nih.gov/pubmed/9230070