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RECEPTORS ON IMMUNOCOMPETENT CELLS : IV. DIRECT MEASUREMENT OF AVIDITY OF CELL RECEPTORS AND COOPERATIVE BINDING OF MULTIVALENT LIGANDS

The interaction of antigen with specific, cell-associated receptors was measured in thermodynamic terms. The binding of (125)I-labeled 2,4-dinitrophenyl guinea pig albumin (DNP(16)GPA-(125)I) to lymphocytes from guinea pigs immunized to DNP(16)GPA is a temperature-dependent, reversible process. Meas...

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Detalles Bibliográficos
Autores principales: Davie, Joseph M., Paul, William E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1972
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139127/
https://www.ncbi.nlm.nih.gov/pubmed/5061978