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ISOLATION OF ANTIGEN-BINDING CELLS FROM UNPRIMED MICE : Demonstration of Antibody-Forming Cell Precursor Activity and Correlation between Precursor and Secreted Antibody Avidities
Cells binding DNP groups conjugated to fluoresceinated mouse gamma globulin ((F)DNP-MGG) were isolated from spleens of unprimed mice using a fluorescence-activated cell sorter (FACS). The isolated cells were specifically enriched at least 100-fold for anti-DNP precursor activity in an adoptive trans...
Autores principales: | Julius, Michael H., Herzenberg, Leonard A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1974
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139630/ https://www.ncbi.nlm.nih.gov/pubmed/4139227 |
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