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Regulation of Tenascin-C, a Vascular Smooth Muscle Cell Survival Factor that Interacts with the α(v)β(3) Integrin to Promote Epidermal Growth Factor Receptor Phosphorylation and Growth
Tenascin-C (TN-C) is induced in pulmonary vascular disease, where it colocalizes with proliferating smooth muscle cells (SMCs) and epidermal growth factor (EGF). Furthermore, cultured SMCs require TN-C for EGF-dependent growth on type I collagen. In this study, we explore the regulation and function...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139818/ https://www.ncbi.nlm.nih.gov/pubmed/9314546 |