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Desmin Is Essential for the Tensile Strength and Integrity of Myofibrils but Not for Myogenic Commitment, Differentiation, and Fusion of Skeletal Muscle

A null mutation was introduced into the mouse desmin gene by homologous recombination. The desmin knockout mice (Des −/−) develop normally and are fertile. However, defects were observed after birth in skeletal, smooth, and cardiac muscles (Li, Z., E. Colucci-Guyon, M. Pincon-Raymond, M. Mericskay,...

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Detalles Bibliográficos
Autores principales: Li, Zhenlin, Mericskay, Mathias, Agbulut, Onnik, Butler-Browne, Gillian, Carlsson, Lena, Thornell, Lars-Eric, Babinet, Charles, Paulin, Denise
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139820/
https://www.ncbi.nlm.nih.gov/pubmed/9314534