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Desmin Is Essential for the Tensile Strength and Integrity of Myofibrils but Not for Myogenic Commitment, Differentiation, and Fusion of Skeletal Muscle
A null mutation was introduced into the mouse desmin gene by homologous recombination. The desmin knockout mice (Des −/−) develop normally and are fertile. However, defects were observed after birth in skeletal, smooth, and cardiac muscles (Li, Z., E. Colucci-Guyon, M. Pincon-Raymond, M. Mericskay,...
Autores principales: | Li, Zhenlin, Mericskay, Mathias, Agbulut, Onnik, Butler-Browne, Gillian, Carlsson, Lena, Thornell, Lars-Eric, Babinet, Charles, Paulin, Denise |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139820/ https://www.ncbi.nlm.nih.gov/pubmed/9314534 |
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