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SOI1 Encodes a Novel, Conserved Protein That Promotes TGN–Endosomal Cycling of Kex2p and Other Membrane Proteins by Modulating the Function of Two TGN Localization Signals

Localization of yeast Kex2 protease to the TGN requires a signal (TLS1) in its cytosolic tail (C-tail). Mutation of TLS1 results in rapid transit of Kex2p to the vacuole. Isolation of suppressors of the Tyr(713)Ala mutation in TLS1 previously identified three SOI genes. SOI1, cloned by complementati...

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Detalles Bibliográficos
Autores principales: Brickner, Jason H., Fuller, Robert S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139830/
https://www.ncbi.nlm.nih.gov/pubmed/9314526