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An Intralysosomal hsp70 Is Required for a Selective Pathway of Lysosomal Protein Degradation

Previous studies have implicated the heat shock cognate (hsc) protein of 73 kD (hsc73) in stimulating a lysosomal pathway of proteolysis that is selective for particular cytosolic proteins. This pathway is activated by serum deprivation in confluent cultured human fibroblasts. We now show, using ind...

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Detalles Bibliográficos
Autores principales: Agarraberes, Fernando A., Terlecky, Stanley R., Dice, J. Fred
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139836/
https://www.ncbi.nlm.nih.gov/pubmed/9151685