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Drosophila TIF-IA is required for ribosome synthesis and cell growth and is regulated by the TOR pathway

Synthesis of ribosomal RNA (rRNA) is a key step in ribosome biogenesis and is essential for cell growth. Few studies, however, have investigated rRNA synthesis regulation in vivo in multicellular organisms. Here, we present a genetic analysis of transcription initiation factor IA (TIF-IA), a conserv...

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Detalles Bibliográficos
Autores principales: Grewal, Savraj S., Evans, Justin R., Edgar, Bruce A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140016/
https://www.ncbi.nlm.nih.gov/pubmed/18086911
http://dx.doi.org/10.1083/jcb.200709044