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Drosophila TIF-IA is required for ribosome synthesis and cell growth and is regulated by the TOR pathway
Synthesis of ribosomal RNA (rRNA) is a key step in ribosome biogenesis and is essential for cell growth. Few studies, however, have investigated rRNA synthesis regulation in vivo in multicellular organisms. Here, we present a genetic analysis of transcription initiation factor IA (TIF-IA), a conserv...
Autores principales: | Grewal, Savraj S., Evans, Justin R., Edgar, Bruce A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140016/ https://www.ncbi.nlm.nih.gov/pubmed/18086911 http://dx.doi.org/10.1083/jcb.200709044 |
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