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Par3 functions in the biogenesis of the primary cilium in polarized epithelial cells

Par3 is a PDZ protein important for the formation of junctional complexes in epithelial cells. We have identified an additional role for Par3 in membrane biogenesis. Although Par3 was not required for maintaining polarized apical or basolateral membrane domains, at the apical surface, Par3 was absol...

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Detalles Bibliográficos
Autores principales: Sfakianos, Jeff, Togawa, Akashi, Maday, Sandra, Hull, Mike, Pypaert, Marc, Cantley, Lloyd, Toomre, Derek, Mellman, Ira
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140027/
https://www.ncbi.nlm.nih.gov/pubmed/18070914
http://dx.doi.org/10.1083/jcb.200709111