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The mitochondrial respiratory chain is a modulator of apoptosis

Mitochondrial dysfunction and dysregulation of apoptosis are implicated in many diseases such as cancer and neurodegeneration. We investigate here the role of respiratory chain (RC) dysfunction in apoptosis, using mitochondrial DNA mutations as genetic models. Although some mutations eliminate the e...

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Detalles Bibliográficos
Autores principales: Kwong, Jennifer Q., Henning, Matthew S., Starkov, Anatoly A., Manfredi, Giovanni
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140029/
https://www.ncbi.nlm.nih.gov/pubmed/18086914
http://dx.doi.org/10.1083/jcb.200704059