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The mitochondrial respiratory chain is a modulator of apoptosis
Mitochondrial dysfunction and dysregulation of apoptosis are implicated in many diseases such as cancer and neurodegeneration. We investigate here the role of respiratory chain (RC) dysfunction in apoptosis, using mitochondrial DNA mutations as genetic models. Although some mutations eliminate the e...
Autores principales: | Kwong, Jennifer Q., Henning, Matthew S., Starkov, Anatoly A., Manfredi, Giovanni |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140029/ https://www.ncbi.nlm.nih.gov/pubmed/18086914 http://dx.doi.org/10.1083/jcb.200704059 |
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