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Dimeric PKD regulates membrane fission to form transport carriers at the TGN

Protein kinase D (PKD) is recruited to the trans-Golgi network (TGN) through interaction with diacylglycerol (DAG) and is required for the biogenesis of TGN to cell surface transport carriers. We now provide definitive evidence that PKD has a function in membrane fission. PKD depletion by siRNA inhi...

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Detalles Bibliográficos
Autores principales: Bossard, Carine, Bresson, Damien, Polishchuk, Roman S., Malhotra, Vivek
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140039/
https://www.ncbi.nlm.nih.gov/pubmed/18086912
http://dx.doi.org/10.1083/jcb.200703166