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A naturally occurring calcineurin variant inhibits FoxO activity and enhances skeletal muscle regeneration

The calcium-activated phosphatase calcineurin (Cn) transduces physiological signals through intracellular pathways to influence the expression of specific genes. Here, we characterize a naturally occurring splicing variant of the CnAβ catalytic subunit (CnAβ1) in which the autoinhibitory domain that...

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Detalles Bibliográficos
Autores principales: Lara-Pezzi, Enrique, Winn, Nadine, Paul, Angelika, McCullagh, Karl, Slominsky, Esfir, Santini, Maria Paola, Mourkioti, Foteini, Sarathchandra, Padmini, Fukushima, Satsuki, Suzuki, Ken, Rosenthal, Nadia
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140042/
https://www.ncbi.nlm.nih.gov/pubmed/18086917
http://dx.doi.org/10.1083/jcb.200704179