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Plasmodium vivax Invasion of Human Erythrocytes Inhibited by Antibodies Directed against the Duffy Binding Protein

BACKGROUND: Plasmodium vivax invasion requires interaction between the human Duffy antigen on the surface of erythrocytes and the P. vivax Duffy binding protein (PvDBP) expressed by the parasite. Given that Duffy-negative individuals are resistant and that Duffy-negative heterozygotes show reduced s...

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Detalles Bibliográficos
Autores principales: Grimberg, Brian T, Udomsangpetch, Rachanee, Xainli, Jia, McHenry, Amy, Panichakul, Tasanee, Sattabongkot, Jetsumon, Cui, Liwang, Bockarie, Moses, Chitnis, Chetan, Adams, John, Zimmerman, Peter A, King, Christopher L
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140086/
https://www.ncbi.nlm.nih.gov/pubmed/18092885
http://dx.doi.org/10.1371/journal.pmed.0040337