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Transglutaminase 2 Undergoes a Large Conformational Change upon Activation
Human transglutaminase 2 (TG2), a member of a large family of enzymes that catalyze protein crosslinking, plays an important role in the extracellular matrix biology of many tissues and is implicated in the gluten-induced pathogenesis of celiac sprue. Although vertebrate transglutaminases have been...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140088/ https://www.ncbi.nlm.nih.gov/pubmed/18092889 http://dx.doi.org/10.1371/journal.pbio.0050327 |