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LFA-1–mediated Adhesion Is Regulated by Cytoskeletal Restraint and by a Ca(2+)-dependent Protease, Calpain

The activity of integrins on leukocytes is kept under tight control to avoid inappropriate adhesion while these cells are circulating in blood or migrating through tissues. Using lymphocyte function-associated antigen-1 (LFA-1) on T cells as a model, we have investigated adhesion to ligand intercell...

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Detalles Bibliográficos
Autores principales: Stewart, Mairi P., McDowall, Alison, Hogg, Nancy
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140165/
https://www.ncbi.nlm.nih.gov/pubmed/9456328