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Haplotype-based score test for linkage in nuclear families

BACKGROUND: To look for genetic linkage between angiotensin-I converting enzyme(ACE) gene and hypertension in a Korean adolescent cohort, we developed a powerful test using the covariances between marginal differences and their variances in a transmission/non-transmission table. RESULTS: We estimate...

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Detalles Bibliográficos
Autores principales: Nam, Chung Mo, Kang, Dae Ryong, Kim, Jinheum
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140270/
https://www.ncbi.nlm.nih.gov/pubmed/17672913
http://dx.doi.org/10.1186/1471-2105-8-277