Novel β-Secretase Cleavage of β-Amyloid Precursor Protein in the Endoplasmic Reticulum/Intermediate Compartment of NT2N Cells

Previous studies have demonstrated that NT2N neurons derived from a human embryonal carcinoma cell line (NT2) constitutively process the endogenous wild-type β-amyloid precursor protein (APP) to amyloid β peptide in an intracellular compartment. These studies indicate that other proteolytic fragment...

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Detalles Bibliográficos
Autores principales: Chyung, Abraham S.C., Greenberg, Barry D., Cook, David G., Doms, Robert W., Lee, Virginia M.-Y.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141643/
https://www.ncbi.nlm.nih.gov/pubmed/9245794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141643/
https://www.ncbi.nlm.nih.gov/pubmed/9245794

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