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Novel β-Secretase Cleavage of β-Amyloid Precursor Protein in the Endoplasmic Reticulum/Intermediate Compartment of NT2N Cells

Previous studies have demonstrated that NT2N neurons derived from a human embryonal carcinoma cell line (NT2) constitutively process the endogenous wild-type β-amyloid precursor protein (APP) to amyloid β peptide in an intracellular compartment. These studies indicate that other proteolytic fragment...

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Detalles Bibliográficos
Autores principales:	Chyung, Abraham S.C., Greenberg, Barry D., Cook, David G., Doms, Robert W., Lee, Virginia M.-Y.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1997
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141643/ https://www.ncbi.nlm.nih.gov/pubmed/9245794

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