Targeting of NH(2)-terminal–processed Microsomal Protein to Mitochondria: A Novel Pathway for the Biogenesis of Hepatic Mitochondrial P450MT2

Cytochrome P4501A1 is a hepatic, microsomal membrane–bound enzyme that is highly induced by various xenobiotic agents. Two NH(2)-terminal truncated forms of this P450, termed P450MT2a and MT2b, are also found localized in mitochondria from β-naphthoflavone–induced livers. In this paper, we demonstra...

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Detalles Bibliográficos
Autores principales: Addya, Sankar, Anandatheerthavarada, Hindupur K., Biswas, Gopa, Bhagwat, Shripad V., Mullick, Jayati, Avadhani, Narayan G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141697/
https://www.ncbi.nlm.nih.gov/pubmed/9348277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141697/
https://www.ncbi.nlm.nih.gov/pubmed/9348277

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