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Specific and Redundant Functions of Retinoid X Receptor/Retinoic Acid Receptor Heterodimers in Differentiation, Proliferation, and Apoptosis of F9 Embryonal Carcinoma Cells

We have generated F9 murine embryonal carcinoma cells in which either the retinoid X receptor (RXR)α and retinoic acid receptor (RAR)α genes or the RXRα and RARγ genes are knocked out, and compared their phenotypes with those of wild-type (WT), RXRα(−/−), RARα(−/−), and RARγ(−/−) cells. RXRα(−/−)/ R...

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Detalles Bibliográficos
Autores principales: Chiba, Hideki, Clifford, John, Metzger, Daniel, Chambon, Pierre
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141719/
https://www.ncbi.nlm.nih.gov/pubmed/9348290