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CAS/Crk Coupling Serves as a “Molecular Switch” for Induction of Cell Migration

Abstract. Carcinoma cells selected for their ability to migrate in vitro showed enhanced invasive properties in vivo. Associated with this induction of migration was the anchorage-dependent phosphorylation of p130CAS (Crk-associated substrate), leading to its coupling to the adaptor protein c-CrkII...

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Detalles Bibliográficos
Autores principales: Klemke, Richard L., Leng, Jie, Molander, Rachel, Brooks, Peter C., Vuori, Kristiina, Cheresh, David A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141747/
https://www.ncbi.nlm.nih.gov/pubmed/9472046