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A Transgenic Myogenic Cell Line Lacking Ryanodine Receptor Protein for Homologous Expression Studies: Reconstitution of Ry(1)R Protein and Function

Abstract. CCS embryonic stem (ES) cells possessing two mutant alleles (ry(1)r−/ry(1)r−) for the skeletal muscle ryanodine receptor (RyR) have been produced and injected subcutaneously into severely compromised immunodeficient mice to produce teratocarcinomas in which Ry(1)R expression is absent. Sev...

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Detalles Bibliográficos
Autores principales: Moore, R.A., Nguyen, H., Galceran, J., Pessah, I.N., Allen, P.D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141755/
https://www.ncbi.nlm.nih.gov/pubmed/9472036