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Blocking Cytochrome c Activity within Intact Neurons Inhibits Apoptosis

Cytochrome c has been shown to play a role in cell-free models of apoptosis. During NGF withdrawal–induced apoptosis of intact rat superior cervical ganglion (SCG) neurons, we observe the redistribution of cytochrome c from the mitochondria to the cytoplasm. This redistribution is not inhibited by t...

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Detalles Bibliográficos
Autores principales: Neame, Stephen J., Rubin, Lee L., Philpott, Karen L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141762/
https://www.ncbi.nlm.nih.gov/pubmed/9744886