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Elevated adipogenesis of marrow mesenchymal stem cells during early steroid-associated osteonecrosis development

BACKGROUND: Increased bone marrow lipid deposition in steroid-associated osteonecrosis (ON) implies that abnormalities in fat metabolism play an important role in ON development. The increase in lipid deposition might be explained by elevated adipogenesis of marrow mesenchymal stem cells (MSCs). How...

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Detalles Bibliográficos
Autores principales: Sheng, Hui H, Zhang, Ge G, Cheung, Wing Hoi WH, Chan, Chun Wai CW, Wang, Yi Xiang YX, Lee, Kwong Man KM, Wang, Hong Fu HF, Leung, Kwok Sui KS, Qin, Ling L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2146995/
https://www.ncbi.nlm.nih.gov/pubmed/17937789
http://dx.doi.org/10.1186/1749-799X-2-15