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Induction of multi-antigen multi-stage immune responses against Plasmodium falciparum in rhesus monkeys, in the absence of antigen interference, with heterologous DNA prime/poxvirus boost immunization

The present study has evaluated the immunogenicity of single or multiple Plasmodium falciparum (Pf) antigens administered in a DNA prime/poxvirus boost regimen with or without the poloxamer CRL1005 in rhesus monkeys. Animals were primed with PfCSP plasmid DNA or a mixture of PfCSP, PfSSP2/TRAP, PfLS...

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Detalles Bibliográficos
Autores principales: Jiang, George, Charoenvit, Yupin, Moreno, Alberto, Baraceros, Maria F, Banania, Glenna, Richie, Nancy, Abot, Steve, Ganeshan, Harini, Fallarme, Victoria, Patterson, Noelle B, Geall, Andrew, Weiss, Walter R, Strobert, Elizabeth, Caro-Aquilar, Ivette, Lanar, David E, Saul, Allan, Martin, Laura B, Gowda, Kalpana, Morrissette, Craig R, Kaslow, David C, Carucci, Daniel J, Galinski, Mary R, Doolan, Denise L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147027/
https://www.ncbi.nlm.nih.gov/pubmed/17925026
http://dx.doi.org/10.1186/1475-2875-6-135