Nitrated α–Synuclein Immunity Accelerates Degeneration of Nigral Dopaminergic Neurons

BACKGROUND: The neuropathology of Parkinson's disease (PD) includes loss of dopaminergic neurons in the substantia nigra, nitrated α-synuclein (N-α-Syn) enriched intraneuronal inclusions or Lewy bodies and neuroinflammation. While the contribution of innate microglial inflammatory activities to...

Descripción completa

Detalles Bibliográficos
Autores principales: Benner, Eric J., Banerjee, Rebecca, Reynolds, Ashley D., Sherman, Simon, Pisarev, Vladimir M., Tsiperson, Vladislav, Nemachek, Craig, Ciborowski, Pawel, Przedborski, Serge, Mosley, R. Lee, Gendelman, Howard E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147051/
https://www.ncbi.nlm.nih.gov/pubmed/18167537
http://dx.doi.org/10.1371/journal.pone.0001376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147051/
https://www.ncbi.nlm.nih.gov/pubmed/18167537
http://dx.doi.org/10.1371/journal.pone.0001376

Ejemplares similares