Bub1 Is a Fission Yeast Kinetochore Scaffold Protein, and Is Sufficient to Recruit other Spindle Checkpoint Proteins to Ectopic Sites on Chromosomes

The spindle checkpoint delays anaphase onset until all chromosomes have attached in a bi-polar manner to the mitotic spindle. Mad and Bub proteins are recruited to unattached kinetochores, and generate diffusible anaphase inhibitors. Checkpoint models propose that Mad1 and Bub1 act as stable kinetoc...

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Detalles Bibliográficos
Autores principales: Rischitor, Patricia E., May, Karen M., Hardwick, Kevin G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147072/
https://www.ncbi.nlm.nih.gov/pubmed/18094750
http://dx.doi.org/10.1371/journal.pone.0001342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147072/
https://www.ncbi.nlm.nih.gov/pubmed/18094750
http://dx.doi.org/10.1371/journal.pone.0001342

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