Cell cycle-specific UNG2 phosphorylations regulate protein turnover, activity and association with RPA

Human UNG2 is a multifunctional glycosylase that removes uracil near replication forks and in non-replicating DNA, and is important for affinity maturation of antibodies in B cells. How these diverse functions are regulated remains obscure. Here, we report three new phosphoforms of the non-catalytic...

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Detalles Bibliográficos
Autores principales: Hagen, Lars, Kavli, Bodil, Sousa, Mirta M L, Torseth, Kathrin, Liabakk, Nina B, Sundheim, Ottar, Peňa-Diaz, Javier, Otterlei, Marit, Hørning, Ole, Jensen, Ole N, Krokan, Hans E, Slupphaug, Geir
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147998/
https://www.ncbi.nlm.nih.gov/pubmed/18079698
http://dx.doi.org/10.1038/sj.emboj.7601958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147998/
https://www.ncbi.nlm.nih.gov/pubmed/18079698
http://dx.doi.org/10.1038/sj.emboj.7601958

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