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Cell cycle-specific UNG2 phosphorylations regulate protein turnover, activity and association with RPA
Human UNG2 is a multifunctional glycosylase that removes uracil near replication forks and in non-replicating DNA, and is important for affinity maturation of antibodies in B cells. How these diverse functions are regulated remains obscure. Here, we report three new phosphoforms of the non-catalytic...
Autores principales: | Hagen, Lars, Kavli, Bodil, Sousa, Mirta M L, Torseth, Kathrin, Liabakk, Nina B, Sundheim, Ottar, Peňa-Diaz, Javier, Otterlei, Marit, Hørning, Ole, Jensen, Ole N, Krokan, Hans E, Slupphaug, Geir |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147998/ https://www.ncbi.nlm.nih.gov/pubmed/18079698 http://dx.doi.org/10.1038/sj.emboj.7601958 |
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