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Kinetic Pathway of Pyrophosphorolysis by a Retrotransposon Reverse Transcriptase

DNA and RNA polymerases use a common phosphoryl transfer mechanism for base addition that requires two or three acidic amino acid residues at their active sites. We previously showed, for the reverse transcriptase (RT) encoded by the yeast retrotransposon Ty1, that one of the three conserved active...

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Detalles Bibliográficos
Autores principales: Pandey, Manjula, Patel, Smita S., Gabriel, Abram
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2148107/
https://www.ncbi.nlm.nih.gov/pubmed/18167548
http://dx.doi.org/10.1371/journal.pone.0001389