Regulation of Bone Morphogenetic Protein Activity by Pro Domains and Proprotein Convertases

Bone morphogenetic proteins (BMPs) are derived from inactive precursor proteins by endoproteolytic cleavage. Here we show that processing of Nodal and Myc-tagged BMP4 is significantly enhanced by SPC1/Furin or SPC4/PACE4, providing direct evidence that regulation of BMP signaling is likely to be con...

Descripción completa

Detalles Bibliográficos
Autores principales: Constam, Daniel B., Robertson, Elizabeth J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2148113/
https://www.ncbi.nlm.nih.gov/pubmed/9885250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2148113/
https://www.ncbi.nlm.nih.gov/pubmed/9885250

Ejemplares similares