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Dissection of the Molecular Basis of pp60(v-src) Induced Gating of Connexin 43 Gap Junction Channels

Suppression of gap-junctional communication by various protein kinases, growth factors, and oncogenes frequently correlates with enhanced mitogenesis. The oncogene v-src appears to cause acute closure of gap junction channels. Tyr265 in the COOH-terminal tail of connexin 43 (Cx43) has been implicate...

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Detalles Bibliográficos
Autores principales: Zhou, Lan, Kasperek, Eileen M., Nicholson, Bruce J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2148195/
https://www.ncbi.nlm.nih.gov/pubmed/10085299