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Occludin-deficient Embryonic Stem Cells Can Differentiate into Polarized Epithelial Cells Bearing Tight Junctions

Occludin is the only known integral membrane protein of tight junctions (TJs), and is now believed to be directly involved in the barrier and fence functions of TJs. Occludin-deficient embryonic stem (ES) cells were generated by targeted disruption of both alleles of the occludin gene. When these ce...

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Detalles Bibliográficos
Autores principales: Saitou, Mitinori, Fujimoto, Kazushi, Doi, Yoshinori, Itoh, Masahiko, Fujimoto, Toyoshi, Furuse, Mikio, Takano, Hiroshi, Noda, Tetsuo, Tsukita, Shoichiro
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2148457/
https://www.ncbi.nlm.nih.gov/pubmed/9548718