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Occludin-deficient Embryonic Stem Cells Can Differentiate into Polarized Epithelial Cells Bearing Tight Junctions
Occludin is the only known integral membrane protein of tight junctions (TJs), and is now believed to be directly involved in the barrier and fence functions of TJs. Occludin-deficient embryonic stem (ES) cells were generated by targeted disruption of both alleles of the occludin gene. When these ce...
Autores principales: | Saitou, Mitinori, Fujimoto, Kazushi, Doi, Yoshinori, Itoh, Masahiko, Fujimoto, Toyoshi, Furuse, Mikio, Takano, Hiroshi, Noda, Tetsuo, Tsukita, Shoichiro |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2148457/ https://www.ncbi.nlm.nih.gov/pubmed/9548718 |
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