Tirapazamine-cisplatin: the synergy.

Tirapazamine is a novel bioreductive agent with selective cytotoxicity against hypoxic tumour cells. Synergy with cisplatin and other chemotherapeutic agents has been shown in preclinical trials. Pharmacokinetic studies of tirapazamine have revealed that exposure increases with dose over the range o...

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Detalles Bibliográficos
Autores principales: Gatzemeier, U., Rodriguez, G., Treat, J., Miller, V., von Roemeling, R., Viallet, J., Rey, A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1998
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2149886/
https://www.ncbi.nlm.nih.gov/pubmed/9647615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2149886/
https://www.ncbi.nlm.nih.gov/pubmed/9647615

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