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Inhibitors of aromatase prevent degradation of the enzyme in cultured human tumour cells.

The effects of two steroidal (4-hydroxyandrostenedione and atamestane) and three non-steroidal (fadrozole, vorozole and pentrozole) aromatase inhibitors on the levels of aromatase mRNA and protein were examined using cultured JEG-3 and HepG2 cells. Immunocytochemical studies demonstrated increased q...

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Detalles Bibliográficos
Autores principales: Harada, N., Hatano, O.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2149917/
https://www.ncbi.nlm.nih.gov/pubmed/9484813