2-(4-Aminophenyl)benzothiazoles: novel agents with selective profiles of in vitro anti-tumour activity.

2-(4-Aminophenyl)benzothiazole (CJM 126) elicits biphasic growth-inhibitory effects against a panel of oestrogen receptor-positive (ER+) and oestrogen receptor-negative (ER-) human mammary carcinoma cell lines in vitro, yielding IC50 values in the nM range. Substitutions adjacent to the amino group...

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Detalles Bibliográficos
Autores principales: Bradshaw, T. D., Wrigley, S., Shi, D. F., Schultz, R. J., Paull, K. D., Stevens, M. F.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1998
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2149949/
https://www.ncbi.nlm.nih.gov/pubmed/9514053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2149949/
https://www.ncbi.nlm.nih.gov/pubmed/9514053

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