Interleukin 2 restores CD3-zeta chain expression but fails to generate tumour-specific lytic activity in tumour-infiltrating lymphocytes derived from human colorectal hepatic metastases.

Metastatic colorectal cancer is usually progressive despite infiltration of the tumours by T lymphocytes, suggesting that these tumour-infiltrating lymphocytes (TILs) are functionally deficient. Recently, TILs from other tumours have been shown to express reduced levels of the T-cell receptor signal...

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Detalles Bibliográficos
Autores principales: Yoong, K. F., Adams, D. H.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1998
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150140/
https://www.ncbi.nlm.nih.gov/pubmed/9569042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150140/
https://www.ncbi.nlm.nih.gov/pubmed/9569042

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