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Wt-p53 action in human leukaemia cell lines corresponding to different stages of differentiation.

Recent studies support the potential application of the wt-p53 gene in cancer therapy. Expression of exogenous wt-p53 suppresses a variety of leukaemia phenotypes by acting on cell survival, proliferation and/or differentiation. As for tumour gene therapy, the final fate of the neoplastic cells is o...

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Detalles Bibliográficos
Autores principales: Rizzo, M. G., Zepparoni, A., Cristofanelli, B., Scardigli, R., Crescenzi, M., Blandino, G., Giuliacci, S., Ferrari, S., Soddu, S., Sacchi, A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150178/
https://www.ncbi.nlm.nih.gov/pubmed/9652758