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Frequent alterations of cell cycle regulators in early-stage breast lesions as detected by immunohistochemistry.
Progression through G1 phase of the eukaryotic cell cycle is tightly controlled by cyclin-dependent kinases (CDK). These proteins form part of a regulatory pathway including the cyclin-dependent kinase inhibitor (CKI) p16, D-type cyclins and the product of the retinoblastoma gene pRb. Aberration of...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
1998
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150197/ https://www.ncbi.nlm.nih.gov/pubmed/9652762 |