The contribution of lactic acid to acidification of tumours: studies of variant cells lacking lactate dehydrogenase.

Solid tumours develop an acidic extracellular environment with high concentration of lactic acid, and lactic acid produced by glycolysis has been assumed to be the major cause of tumour acidity. Experiments using lactate dehydrogenase (LDH)-deficient ras-transfected Chinese hamster ovarian cells hav...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamagata, M., Hasuda, K., Stamato, T., Tannock, I. F.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1998
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150353/
https://www.ncbi.nlm.nih.gov/pubmed/9667639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150353/
https://www.ncbi.nlm.nih.gov/pubmed/9667639

Ejemplares similares