Toxicity to neuroblastoma cells and spheroids of benzylguanidine conjugated to radionuclides with short-range emissions.

Radiolabelled meta-iodobenzylguanidine (MIBG) is selectively taken up by tumours of neuroendocrine origin, where its cellular localization is believed to be cytoplasmic. The radiopharmaceutical [131I]MIBG is now widely used in the treatment of neuroblastoma, but other radioconjugates of benzylguanid...

Descripción completa

Detalles Bibliográficos
Autores principales: Cunningham, S. H., Mairs, R. J., Wheldon, T. E., Welsh, P. C., Vaidyanathan, G., Zalutsky, M. R.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1998
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150394/
https://www.ncbi.nlm.nih.gov/pubmed/9649115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150394/
https://www.ncbi.nlm.nih.gov/pubmed/9649115

Ejemplares similares